Blockage of dopaminergic D(2) receptors produces decrease of REM but not of slow wave sleep in rats after REM sleep deprivation.

@article{Lima2008BlockageOD,
  title={Blockage of dopaminergic D(2) receptors produces decrease of REM but not of slow wave sleep in rats after REM sleep deprivation.},
  author={Marcelo M S Lima and M{\^o}nica Levy Andersen and Angela Braga Reksidler and Andressa Silva and Adriano Zager and S{\'i}lvio Marques Zanata and Maria Aparecida Barbato Fraz{\~a}o Vital and Sergio Brasil Tufik},
  journal={Behavioural brain research},
  year={2008},
  volume={188 2},
  pages={406-11}
}
Dopamine (DA) has, as of late, become singled out from the profusion of other neurotransmitters as what could be called a key substance, in the regulation of the sleep-wake states. We have hypothesized that dopaminergic D(2) receptor blockage induced by haloperidol could generate a reduction or even an ablation of rapid eye movement (REM) sleep. Otherwise, the use of the selective D(2) agonist, piribedil, could potentiate REM sleep. Electrophysiological findings demonstrate that D(2) blockage… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
18 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 18 extracted citations

Similar Papers

Loading similar papers…