Blockade of excitatory neurotransmission in the globus pallidus induces rigidity and akinesia in the rat: implications for excitatory neurotransmission in pathogenesis of Parkinson's diseases

@article{Turski1990BlockadeOE,
  title={Blockade of excitatory neurotransmission in the globus pallidus induces rigidity and akinesia in the rat: implications for excitatory neurotransmission in pathogenesis of Parkinson's diseases},
  author={Lechosław Turski and Thomas Klockgether and Waldemar A. Turski and Michael Schwarz and K-H. Sontag},
  journal={Brain Research},
  year={1990},
  volume={512},
  pages={125-131}
}
Evidence for Functional Differences between Entopeduncular Nucleus and Substantia Nigra: Effects of APV (DL‐2‐amino‐5‐phosphonovaleric acid) Microinfusion on Reaction Time Performance in the Rat
TLDR
The results reveal that the different functional weight of the three main output pathways originating at the STN level is t.o.o., and regarding the differential effects produced by the same dose of APV in the SNr and the EP, these two structures, which are classically believed to be functionally linked should not be considered as the same functional entity in the organization of basal ganglia outflow.
Characterisation of striatal NMDA receptors involved in the generation of parkinsonian symptoms: Intrastriatal microinjection studies in the 6‐OHDA‐lesioned rat
  • J. Nash, J. Brotchie
  • Biology, Psychology
    Movement disorders : official journal of the Movement Disorder Society
  • 2002
TLDR
It is proposed that stimulation of NR2B‐containing NMDA receptors in the rostral striatum underlies the generation of parkinsonian symptoms.
Interaction of galanin receptors with glutamate receptors in the neostriatum: a neuropharmacological analysis
TLDR
It is made that galanin potentiates specific behavioral and motor effects of KA injected into the striatum, and this interaction is due to the modulatory influence of the peptide on the receptors to endogenous opioids, excitatory amino acids, or acetylcholine.
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