Blockade of colony stimulating factor-1 (CSF-I) leads to inhibition of DSS-induced colitis.


BACKGROUND Intestinal inflammation associated with inflammatory bowel disease (IBD) is typically characterized by an inflammatory cell infiltrate and pro-inflammatory cytokine production. Of particular interest, the frequency of colony stimulating factor-1 (CSF-l)-expressing cells is increased in active lesions. In this study, we have investigated the role… (More)


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