Blockade of central and peripheral luteinizing hormone-releasing hormone (LHRH) receptors in neonatal rats with a potent LHRH-antagonist inhibits the morphofunctional development of the thymus and maturation of the cell-mediated and humoral immune responses.

@article{Morale1991BlockadeOC,
  title={Blockade of central and peripheral luteinizing hormone-releasing hormone (LHRH) receptors in neonatal rats with a potent LHRH-antagonist inhibits the morphofunctional development of the thymus and maturation of the cell-mediated and humoral immune responses.},
  author={Maria Concetta Morale and Nunzio Batticane and Giovanni Bartoloni and V Guarcello and Zelinda Farinella and Maria Grazia Galasso and Bianca Marchetti},
  journal={Endocrinology},
  year={1991},
  volume={128 2},
  pages={1073-85}
}
The development of the thymus and the hypothalamic-pituitary-gonadal axis are linked by bidirectional hormonally mediated relationships. In the present study, the direct involvement of the neuropeptide LHRH in the maturation of the thymus and development of the cell-mediated and humoral immune responses were assessed after treatment of neonatal (from post… CONTINUE READING