Blockade of NMDA receptors in the nucleus accumbens elicits spontaneous tail-flicks in rats.

@article{Millan2000BlockadeON,
  title={Blockade of NMDA receptors in the nucleus accumbens elicits spontaneous tail-flicks in rats.},
  author={M. Millan and V. Audinot and P. Honore and K. Bervoets and S. Veiga and M. Brocco},
  journal={European journal of pharmacology},
  year={2000},
  volume={388 1},
  pages={
          37-47
        }
}
The open channel blocker at N-methyl-D-aspartate (NMDA) receptors, dizocilpine, stereospecifically elicited spontaneous tail-flicks in rats - a reaction similar to those elicited by other drugs (tenocyclidine, phencyclidine and ketamine) acting as open channel blockers. Their relative potencies were strongly correlated with affinities at NMDA binding sites and labeled by [3H]dizocilpine in the frontal cortex (r=0.94) and, as determined previously [Millan, M. J., Seguin, L., 1994. Chemically… Expand
Antinociceptive effect of intracerebroventricular administration of d-serine on formalin-induced pain
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