Blockade of NK-1 receptors in the lateral commissural nucleus tractus solitarii of awake rats had no effect on the cardiovascular responses to chemoreflex activation.

@article{Zhang2000BlockadeON,
  title={Blockade of NK-1 receptors in the lateral commissural nucleus tractus solitarii of awake rats had no effect on the cardiovascular responses to chemoreflex activation.},
  author={Cuihua Zhang and Leni G H Bonagamba and Benedito H Machado},
  journal={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
  year={2000},
  volume={33 11},
  pages={1379-85}
}
The neurotransmission of the chemoreflex in the nucleus tractus solitarii (NTS), particularly of the sympatho-excitatory component, is not completely understood. There is evidence that substance P may play a role in the neurotransmission of the chemoreflex in the NTS. Microinjection of substance P (50 pmol/50 nl, N = 12, and 5 nmol/50 nl, N = 8) into the commissural NTS of unanesthetized rats produced a significant increase in mean arterial pressure (101 +/- 1 vs 108 +/- 2 and 107 +/- 3 vs 115… CONTINUE READING
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Substance P and neurotransmission of the baro- and chemoreflex in the nucleus tractus solitarii of unanesthetized rats

  • CH Zhang, LGH Bonagamba, BH Machado
  • Journal of the Autonomic Nervous System,
  • 1997

The Rat Brain in Stereotaxic Coordinates

  • G Paxinos, C Watson
  • 1996

croinjection of NMDA antagonist into the NTS of conscious rats blocks the Bezold - Jarisch reflex

  • BH Machado
  • Brain Research
  • 1996

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