Blockade of CD154-CD40 pathway induces interleukin-10 dependent T regulatory type 1 like cells.

@article{Cai2006BlockadeOC,
  title={Blockade of CD154-CD40 pathway induces interleukin-10 dependent T regulatory type 1 like cells.},
  author={Yong Cai and Yi-rong Yang and Peng Xia and Shao-ling Zheng},
  journal={Chinese medical journal},
  year={2006},
  volume={119 6},
  pages={518-22}
}
everal subsets of T-regulatory (Tr) cells with distinct phenotypes and distinct mechanisms of action have been identified. These include Tr type 1 (Tr1) cells; Th3 cells, which primarily secrete transforming growth factor (TGF)-β; and CD4CD25 T cells, which inhibit immune responses through cell to cell contact. It has been shown that CD4CD25… CONTINUE READING