Blockade of B7-H1 improves myeloid dendritic cell–mediated antitumor immunity


Suppression of dendritic cell function in cancer patients is thought to contribute to the inhibition of immune responses and disease progression. Molecular mechanisms of this suppression remain elusive, however. Here, we show that a fraction of blood monocyte-derived myeloid dendritic cells (MDCs) express B7-H1, a member of the B7 family, on the cell… (More)
DOI: 10.1038/nm863


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