Blinding decreased recruitment in a prevention trial of postmenopausal hormone therapy.

@article{Hemminki2004BlindingDR,
  title={Blinding decreased recruitment in a prevention trial of postmenopausal hormone therapy.},
  author={Elina Hemminki and S L Hovi and Piret Veerus and Tiina Sev{\'o}n and Risto Tuimala and Mati Rahu and Matti Hakama},
  journal={Journal of clinical epidemiology},
  year={2004},
  volume={57 12},
  pages={1237-43}
}
PURPOSE To compare the effect of blind design (active drug and placebo) and nonblind design (active drug and no treatment) on recruitment. SETTING A primary prevention trial with postmenopausal hormone therapy in Estonia. METHODS Women who were eligible and willing to participate on the basis of the questionnaire survey were randomized into blind and nonblind groups. Recruitment rates are based on record keeping, and reasons for participating were requested in the first-year follow-up… CONTINUE READING