Blind source unmixing in multi-spectral optoacoustic tomography.

  title={Blind source unmixing in multi-spectral optoacoustic tomography.},
  author={J{\"u}rgen Glatz and Nikolaos Deliolanis and Andreas Buehler and Daniel Razansky and Vasilis Ntziachristos},
  journal={Optics express},
  volume={19 4},
Multispectral optoacoustic (photoacoustic) tomography (MSOT) is a hybrid modality that can image through several millimeters to centimeters of diffuse tissues, attaining resolutions typical of ultrasound imaging. The method can further identify tissue biomarkers by decomposing the spectral contributions of different photo-absorbing molecules of interest. In this work we investigate the performance of blind source unmixing methods and spectral fitting approaches in decomposing the contributions… CONTINUE READING


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