Bleomycin-lidocaine mixture reduces pain of intralesional injection in the treatment of recalcitrant verrucae.

@article{Manz1991BleomycinlidocaineMR,
  title={Bleomycin-lidocaine mixture reduces pain of intralesional injection in the treatment of recalcitrant verrucae.},
  author={L A Manz and J M Pelachyk},
  journal={Journal of the American Academy of Dermatology},
  year={1991},
  volume={25 3},
  pages={524-6}
}
Intralesional bleomycin has been effective treatment of recalcitrant verrucae since 1970, but one major drawback is the moderate to severe pain associated with the injection. To minimize procedural discomfort, bleomycin can be reconstituted in lidocaine. It is effective, associated with minimal morbidity, and well tolerated by most patients. 

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