Bleeding disorder (von Willebrand disease) in a quarter horse.

  title={Bleeding disorder (von Willebrand disease) in a quarter horse.},
  author={M C Brooks and Gayle S Leith and Anthony K. Allen and P R Woods and Robert E Benson and Wylie J. Dodds},
  journal={Journal of the American Veterinary Medical Association},
  volume={198 1},
Bleeding diathesis in a Quarter Horse filly was caused by von Willebrand disease. Hemorrhage occurred mainly from mucosal surfaces and after trauma. Quantitative and qualitative measurements of plasma von Willebrand factor (vWF) documented a specific deficiency of vWF high molecular weight multimers, and concurrently greater than expected deficiency of vWF activity relative to vWF concentration. These findings are characteristic of type-II von Willebrand disease in human beings. Application of… CONTINUE READING