Bleeding diathesis in Noonan syndrome: a common association.


The Noonan syndrome (NS) is a multiple congenital anomalies (MCA) syndrome with well-known manifestations. Excessive bleeding has been described occasionally. We report on 19 patients with NS and a bleeding diathesis. Several different defects are identified in the coagulation and platelet systems occurring singly or in combination. Clinical expression is… (More)


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@article{Witt1988BleedingDI, title={Bleeding diathesis in Noonan syndrome: a common association.}, author={Dawn R. Witt and Barbara McGillivray and Jessica Allanson and Heather Hughes and William E. Hathaway and Amy R. Zipursky and Judith G. Hall}, journal={American journal of medical genetics}, year={1988}, volume={31 2}, pages={305-17} }