Bleach Activates a Redox-Regulated Chaperone by Oxidative Protein Unfolding

@inproceedings{Schultz2008BleachAA,
  title={Bleach Activates a Redox-Regulated Chaperone by Oxidative Protein Unfolding},
  author={Daniel W. Schultz and Aleksandra M. Walczakl and N. Onuchic and Peter G. Wolynes},
  year={2008}
}
We synthesized tiny stable silver nanoparticles (2.6 f 1 .I nm) and used its small surface area and functional groups to control single molecule detection (SMD) volumes on single nanoparticles. These new approaches allowed us to develop intrinsic single molecule nanoparticle optical biosensors (SMNOBS) for sensing and imaging of single human cytokine molecules, recombinant human tumor necrosis factor-a (TNFa), and probing its binding reaction with single monoclonal antibody (MAB) molecules in… CONTINUE READING
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