Blastocyst development after sperm selection at high magnification is associated with size and number of nuclear vacuoles.

@article{Vanderzwalmen2008BlastocystDA,
  title={Blastocyst development after sperm selection at high magnification is associated with size and number of nuclear vacuoles.},
  author={Pierre Vanderzwalmen and Antje Hiemer and Paul Rubner and Magnus Bach and Anton Neyer and Astrid Stecher and Petr Uher and Martin Zintz and Bernard Lejeune and Sabine Vanderzwalmen and Guy Cassuto and Nicolas Herbert Zech},
  journal={Reproductive biomedicine online},
  year={2008},
  volume={17 5},
  pages={
          617-27
        }
}
Spermatozoa selection at high magnification before intracytoplasmic sperm injection seems to be positively associated with pregnancy rates after day 3 embryo transfers. The aim was to demonstrate an association between the presence of vacuoles in sperm nuclei and the competence of embryos to develop to day 5. Grading of spermatozoa at x 6000-x 12,500 magnification: grade I, no vacuoles; grade II, <or=2 small vacuoles; grade III, >or=1 large vacuole; grade IV, large vacuoles with other… CONTINUE READING
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