Molecular virulence determinants of Magnaporthe oryzae: disease pathogenesis and recent interventions for disease management in rice plant
- Medicine, BiologyMycology
A major concern for the loss in yield of rice crop across the globe, Magnaporthe oryzae, causative agent of the rice blast disease, is a major concern.
Using a hybrid read-across method to evaluate chemical toxicity based on chemical structure and biological data.
- BiologyEcotoxicology and environmental safety
A cotransformation system of the unicellular red alga Cyanidioschyzon merolae with blasticidin S deaminase and chloramphenicol acetyltransferase selectable markers
- BiologyBMC plant biology
A nuclear targeting and transformant selection system using an antibiotics blasticidin S and the BS deaminase selectable marker by homologous recombination is developed and simultaneously modifying two different chromosomal loci by a single-step cotransformation based on the combination of BSD and CAT selectable markers.
A [3Fe-4S] cluster and tRNA-dependent aminoacyltransferase BlsK in the biosynthesis of Blasticidin S
- Biology, ChemistryProceedings of the National Academy of Sciences
The characterization of a new class of aminoacyl-tRNA (aa-t RNA)–dependent enzyme, BlsK, from Streptomyces griseochromogenes is presented, which contains a [3Fe-4S] cluster that is necessary for its function and unprecedented in previously identified tRNA-dependent transferases.
(Accepted/In press). Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA. Nucleic Acids Research
Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA
- BiologyNucleic acids research
It is shown that BlaS inhibits both translation elongation and termination in Mammalia, and modulates translation dynamics at premature termination codons leading to enhanced protein production in human cells.
Microparticles enhance the formation of seven major classes of natural products in native and metabolically engineered actinobacteria through accelerated morphological development
- BiologyBiotechnology and bioengineering
Adding inorganic talc microparticles to cultures of recombinant Streptomyces lividans enhanced production of the macrocyclic peptide antibiotic bottromycin A2 and its methylated derivative Met‐bottromycin a2 up to 109 mg L−1, the highest titer reported so far, and fundamentally affected metabolism.
Streptomyces-based cell factories for production of biomolecules and bioactive metabolites
- Biology, Engineering
Antibacterial Activity of Streptomyces sp. J46 against Bacterial Shot Hole Disease Pathogen Xanthomonas arboricola pv. pruni
BACKGROUND: Bacterial shot hole of stone fruits is a seriuos plant disease caused by Xanthomonas arboricola pv. pruni (Xap). Techniques to control the disease are required. In this study,…
A Streptomyces morookaensis strain promotes plant growth and suppresses Fusarium wilt of banana
- BiologyTropical Plant Pathology
The findings suggest that the Streptomyces morookaensis strain Sm4-1986 could be explored for uses such as biocontrol agents or biofertilizers in banana plantation.