Blarina toxin, a mammalian lethal venom from the short-tailed shrew Blarina brevicauda: Isolation and characterization.

@article{Kita2004BlarinaTA,
  title={Blarina toxin, a mammalian lethal venom from the short-tailed shrew Blarina brevicauda: Isolation and characterization.},
  author={Masaki Kita and Yasuo Nakamura and Yuushi Okumura and Satoshi D. Ohdachi and Yuichi Oba and Michiyasu Yoshikuni and Hiroshi Kido and Daisuke Uemura},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2004},
  volume={101 20},
  pages={7542-7}
}
  • Masaki Kita, Yasuo Nakamura, +5 authors Daisuke Uemura
  • Published 2004 in
    Proceedings of the National Academy of Sciences…
Venomous mammals are rare, and their venoms have not been characterized. We have purified and characterized the blarina toxin (BLTX), a lethal mammalian venom with a tissue kallikrein-like activity from the submaxillary and sublingual glands of the short-tailed shrew Blarina brevicauda. Mice administered BLTX i.p. developed irregular respiration, paralysis, and convulsions before dying. Based on the amino acid sequence of purified protein, we cloned the BLTX cDNA. It consists of a prosequence… CONTINUE READING

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