Blank Correction in Isotope Dilution.

@article{Pagliano2015BlankCI,
  title={Blank Correction in Isotope Dilution.},
  author={Enea Pagliano and Zolt{\'a}n Mester and Juris Meija},
  journal={Analytical chemistry},
  year={2015},
  volume={87 21},
  pages={10724-7}
}
A novel method for compensation of the procedural blank in isotope dilution is presented. This method, entitled "blank-matching", copes with the blank through experimental design. Both sample and calibration solutions are exposed to the same amount of isotopic standard and same procedural blank. The identical treatment of sample and calibrators eliminates the need for subtracting the procedural blank from the result obtained by isotope dilution. A further advantage of the method is that… CONTINUE READING