Bladder surface glycosaminoglycans is a human epithelial permeability barrier.

@article{Lilly1990BladderSG,
  title={Bladder surface glycosaminoglycans is a human epithelial permeability barrier.},
  author={James David Lilly and Charles L. Parsons},
  journal={Surgery, gynecology & obstetrics},
  year={1990},
  volume={171 6},
  pages={
          493-6
        }
}
Transitional epithelium of the bladder has been known to be impermeable. The data reported herein suggest the principal barrier to permeability may be glycosaminoglycans (GAG) of the surface of the bladder. We examined the ability of surface GAG to prevent a small molecule, urea, from moving across the epithelium in humans. It appears that GAG provide a physical barrier which prevents small molecules from reaching the underlying tight junctions and cell membranes and, hence, are a major… CONTINUE READING

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