Bladder cancer

@article{Kaufman2009BladderC,
  title={Bladder cancer},
  author={Donald S. Kaufman and William U. Shipley and Adam S. Feldman},
  journal={The Lancet},
  year={2009},
  volume={374},
  pages={239-249}
}
Bladder cancer.
  • P. Clark
  • Medicine
    Current opinion in oncology
  • 2007
TLDR
Although great strides continue to be made each year in the diagnosis and management of bladder cancer considerably more work needs to be done in order to improve the lives of patients with this disease.
Diagnosis and staging of bladder cancer.
Urinary biomarkers for surveillance of non-muscle invasive bladder cancer
TLDR
Urinary biomarkers for surveillance of nonmuscle invasive bladder cancer have several potential applications including: 1) diagnosing BC in patients presenting with haematuria, 2) detecting recurrences and progression in patients treated for NMIBC, 3) assessing response to Bacillus Calmette-Guerin treatment and 4) as an adjunct in cases whereby cytology is equivocal.
Are we making significant progress in the diagnosis and management of bladder cancer?
Urothelial bladder cancer progression: lessons learned from the bench
TLDR
Research into novel putative biomarkers of progression and chemoresistance that encompass several hallmarks of cancer: tumor neovascularization, invasion and metastasis, and energy metabolism reprogramming of the tumor microenvironment are summarized.
Improving Systemic Chemotherapy for Bladder Cancer
TLDR
It is an extremely exciting time for BCa research, and much needed improvements in systemic treatment are most certainly on the horizon.
Selective bilateral internal iliac artery embolization for controlling refractory hematuria due to the metastatic squamous cell carcinoma of the urinary bladder: a case report
TLDR
An 83-year-old man, a known case of forehead cutaneous SCC with distant metastasis, referred to the clinic with a chief complaint of hematuria and angiography and embolization resulted in complete alleviation of the symptoms.
Low RKIP expression associates with poor prognosis in bladder cancer patients
TLDR
Low RKIP expression was associated with poorer 5-year disease-free and overall survival rates, and remained as an independent prognostic factor for disease- free survival.
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References

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The role of Ras superfamily proteins in bladder cancer progression.
TLDR
The findings discussed offer the hopeful possibility that signaling pathways mediated by Ras superfamily members may offer new opportunities for diagnostic and therapeutic interventions in bladder cancer.
Mechanisms of Disease: genetic and epigenetic alterations that drive bladder cancer
TLDR
A model for the mechanisms behind bladder cancer development is proposed and global trends of increased genomic instability and aberrant methylation of cytosine residues in DNA correlate with increased tumor invasion and progression.
Bladder cancer.
  • H. Ozen
  • Biology, Medicine
    Current opinion in oncology
  • 1998
TLDR
It is postulated that the loss of the function of wild-type p53 allows cells with DNA damage to proceed through the cell cycle, replicating genetic errors, and thus decreased pRb expression in bladder cancer correlates with increased mitotic index.
Molecular characterization of early-stage bladder carcinomas by expression profiles, FGFR3 mutation status, and loss of 9q
TLDR
The combined analyses suggest the existence of two types of UCC tumors, one which is characterized by FGFR3 mutation or expression, high expression of protein synthesis genes, and low expression of cell cycle genes.
The p53 tumor suppressor gene and nuclear protein: basic science review and relevance in the management of bladder cancer.
TLDR
The basic constitutive functions of p53 are outlined, its current role in the management of transitional cell carcinoma of the bladder appears somewhat limited, and the importance of p 53 mutation in tumor cell biology is irrefutable.
Association between smoking and risk of bladder cancer among men and women.
TLDR
Compared with a pooled estimate of US data from cohorts initiated between 1963 and 1987, relative risks for smoking in the more recent NIH-AARP Diet and Health Study cohort were higher, with PARs for women comparable with those for men.
Focus on bladder cancer.
Bladder Cancer in Women
  • J. Baniel
  • Medicine
    International Urogynecology Journal
  • 1999
TLDR
In women bladder cancer usually occurs above the age of 60 and comprises 3% of all female cancers, which must be investigated by radiological imaging and cystoscopy, and management of invasive disease warrants extensive surgery, which is the best single treatment modality.
Genetic Testing Information • What is genetic testing? /primer/testing/genetictesting • Genetic Testing Registry: Bladder carcinoma
    The p 53 tumor suppressor gene and nuclear protein : basic science review and relevance in the management of bladder cancer
    • J Urol
    • 2003
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