46 Citations
Black cohosh (Cimicifuga racemosa) for menopausal symptoms: a systematic review of its efficacy.
- MedicinePharmacological research
- 2008
Phytoestrogens in Postmenopause: The State of the Art from a Chemical, Pharmacological and Regulatory Perspective
- MedicineCurrent medicinal chemistry
- 2014
The clinical scenario underlying the increased interest on phytoestrogens is outlined, by overviewing the evolution of the evidence on HRT and its main therapeutic goals, and available evidence on their riskbenefit profile is put in a regulatory perspective, in light of the recent regulation on health claims of food supplements.
Effects of herbal preparations on symptom clusters during the menopausal transition
- PsychologyClimacteric : the journal of the International Menopause Society
- 2015
Black cohosh mixed with other herbals, Rheum rhaponticum, and French maritime pine bark had significant effects on hot flushes and at least one other symptom and may be a promising alternative treatment to hormonal treatment.
The antiestrogenic effects of black cohosh on BRCA1 and steroid receptors in breast cancer cells
- Biology, MedicineBreast cancer
- 2019
Black Cohosh demonstrates substantial anti-cancer properties, and this study may significantly aid in the understanding of the molecular effects of BC on ER-α, PR, and BRCA1 in breast cancer cells.
Ginseng as a Complementary and Alternative Medicine for Postmenopausal Symptoms
- Biology, Chemistry
- 2009
Ginseng is a popular herbal medicine that has been used for thousands of years. A number of its components have been isolated and characterized, including ginsenosides, polysaccharides, peptides,…
Effects of red ginseng supplementation on menopausal symptoms and cardiovascular risk factors in postmenopausal women: a double-blind randomized controlled trial
- MedicineMenopause
- 2012
RG could be an attractive herbal dietary supplement for relieving menopausal symptoms and conferring favorable effects on markers of cardiovascular disease in postmenopausal women.
Gene expression profiling reveals effects of Cimicifuga racemosa (L.) NUTT. (black cohosh) on the estrogen receptor positive human breast cancer cell line MCF-7
- BiologyBMC pharmacology
- 2007
No estrogenic but antiproliferative and proapoptotic gene expression was shown for black cohosh in MCF-7 cells at the transcriptional level, and the cycloartane glycosides and – for the first time – their aglycons could be identified as an active principle in black cohOSH.
PHARMACOKINETIC DRUG-HERBAL DIETARY SUPPLEMENTS INTERACTIONS CLINICALLY SIGNIFICANT
- Medicine, Biology
- 2014
D dosage forms containing standardized herbal extracts, when administered at per label recommended doses, do not pose a risk for clinically relevant herb-drug interactions, however, daily doses exceeding these doses or prolonged treatment may increase prospects for interactions.
References
SHOWING 1-10 OF 61 REFERENCES
Phytoestrogen therapy for menopausal symptoms?
- Medicine, BiologyBMJ : British Medical Journal
- 2001
More recent intervention studies question the validity of the proposed benefits of phytoestrogen supplementation, with little data in postmenopausal women to support a role for phy toestrogens as an alternative to conventional hormone replacement therapy.
Phytoestrogen supplements for the treatment of hot flashes: the Isoflavone Clover Extract (ICE) Study: a randomized controlled trial.
- Medicine, PsychologyJAMA
- 2003
Although the study provides some evidence for a biological effect of Promensil, neither supplement had a clinically important effect on hot flashes or other symptoms of menopause.
A Randomized Placebo‐Controlled Crossover Trial With Phytoestrogens in Treatment of Menopause in Breast Cancer Patients
- MedicineObstetrics and gynecology
- 2003
Efficacy and Safety of Isopropanolic Black Cohosh Extract for Climacteric Symptoms
- MedicineObstetrics and gynecology
- 2005
This isopropanolic extract of black cohosh root stock is effective in relieving Climacteric symptoms, especially in early climacteric women.
Phytoestrogens and the menopause.
- MedicineClimacteric : the journal of the International Menopause Society
- 1998
An epidemiological background to phytoestrogens, a brief description of their composition and biochemistry, and an overview of the literature to date on phy toestrogens with an emphasis on relief of menopausal symptoms are provided.
Phytoestrogens do not influence lipoprotein levels or endothelial function in healthy, postmenopausal women.
- MedicineThe American journal of cardiology
- 2000
Benefits of Soy Isoflavone Therapeutic Regimen on Menopausal Symptoms
- MedicineObstetrics and gynecology
- 2002
This study suggests that isoflavone 100‐mg regime treatment may be a safe and effective alternative therapy for menopausal symptoms and may offer a benefit to the cardiovascular system.
Effects of dietary phytoestrogens in postmenopausal women.
- MedicineClimacteric : the journal of the International Menopause Society
- 1998
The data obtained from separate analysis suggest that phytoestrogens in soy and linseed may be of use in ameliorating some of the symptoms of menopause, and a significant decrease in hot flush rate in the wheat group cannot be attributable to phy toestrogens measured in this study.
Effects on menopausal symptoms and acceptability of isoflavone-containing soy powder dietary supplementation
- MedicineClimacteric : the journal of the International Menopause Society
- 2001
Powdered energy drinks are not commonly consumed in Australia and were poorly tolerated in this study, suggesting that other methods of isoflavone delivery may be more appropriate in this culture, in future trials.
Soy protein and isoflavone effects on vasomotor symptoms in peri- and postmenopausal women: the Soy Estrogen Alternative Study
- MedicineMenopause
- 2003
It is suggested that soy protein containing 42 or 58 mg of isoflavones is no more effective than is oflavone-extracted soy protein for improving the number and severity of vasomotor symptoms in peri- and postmenopausal women.