Black beetle virus: propagation in Drosophila line 1 cells and an infection-resistant subline carrying endogenous black beetle virus-related particles.

@article{Friesen1980BlackBV,
  title={Black beetle virus: propagation in Drosophila line 1 cells and an infection-resistant subline carrying endogenous black beetle virus-related particles.},
  author={Paul D. Friesen and Paul Scotti and James W. Longworth and Ren{\'e} R{\"u}ckert},
  journal={Journal of virology},
  year={1980},
  volume={35 3},
  pages={741-7}
}
Black beetle virus (BBV), one of a recently discovered class of viruses with a bipartite genome, multiplied readily in Schneider's line 1 of Drosophila cells. Virus yields, on the order of 100 mg per liter of culture, were unusually high and represented some 20% of the total cell protein within 3 days after infection. A derivative subline of these Drosophila cells was found to be resistant to infection by BBV. These resistant cells were also found to carry small amounts of BBV-related particles… CONTINUE READING

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