Bivariate analysis of sensitivity and specificity produces informative summary measures in diagnostic reviews.

Abstract

BACKGROUND AND OBJECTIVES Studies of diagnostic accuracy most often report pairs of sensitivity and specificity. We demonstrate the advantage of using bivariate meta-regression models to analyze such data. METHODS We discuss the methodology of both the summary Receiver Operating Characteristic (sROC) and the bivariate approach by reanalyzing the data of a… (More)

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