Bivalent Compound 17MN Exerts Neuroprotection through Interaction at Multiple Sites in a Cellular Model of Alzheimer's Disease.

Abstract

Multiple pathogenic factors have been suggested to play a role in the development of Alzheimer's disease (AD). The multifactorial nature of AD also suggests the potential use of compounds with polypharmacology as effective disease-modifying agents. Recently, we have developed a bivalent strategy to include cell membrane anchorage into the molecular design… (More)
DOI: 10.3233/JAD-150242

Topics

7 Figures and Tables

Cite this paper

@article{Liu2015BivalentC1, title={Bivalent Compound 17MN Exerts Neuroprotection through Interaction at Multiple Sites in a Cellular Model of Alzheimer's Disease.}, author={Kai Liu and Jeremy E Chojnacki and Emily E. Wade and John M Saathoff and Edward J. Lesnefsky and Qun Chen and Shijun Zhang}, journal={Journal of Alzheimer's disease : JAD}, year={2015}, volume={47 4}, pages={1021-33} }