Bistranded oxidized purine damage clusters: induced in DNA by long-wavelength ultraviolet (290-400 nm) radiation?

@article{Song2002BistrandedOP,
  title={Bistranded oxidized purine damage clusters: induced in DNA by long-wavelength ultraviolet (290-400 nm) radiation?},
  author={J. Song and J. Milligan and B. Sutherland},
  journal={Biochemistry},
  year={2002},
  volume={41 27},
  pages={
          8683-8
        }
}
Bistranded clustered DNA damages involving oxidized bases, abasic sites, and strand breaks are produced by ionizing radiation and radiomimetic drugs, but it was not known whether they can be formed by other agents, e.g., nonionizing radiation. UV radiation produces clusters of cyclobutyl pyrimidine dimers, photoproducts that occur individually in high yield. Since long-wavelength UV (290-400 nm) radiation induces oxidized bases, abasic sites, and strand breaks at low yields, we tested whether… Expand
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References

SHOWING 1-10 OF 49 REFERENCES
Wavelength dependence of ultraviolet-induced DNA damage distribution: involvement of direct or indirect mechanisms and possible artefacts.
  • 214
A study of endonuclease III-sensitive sites in irradiated DNA: detection of alpha-particle-induced oxidative damage.
  • 73
  • PDF
Clustered damages and total lesions induced in DNA by ionizing radiation: oxidized bases and strand breaks.
  • 204
Abortive base-excision repair of radiation-induced clustered DNA lesions in Escherichia coli
  • J. O. Blaisdell, S. Wallace
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 2001
  • 205
  • PDF
Oxidation of Guanine in Cellular DNA by Solar UV Radiation: Biological Role †
  • 119
In vitro Photooxidation of Nucleic Acids by Ultraviolet A Radiation
  • 74
Effect of UV irradiation at defined wavelengths on the tertiary structure of double-stranded covalently closed circular DNA.
  • 19
DNA sequence dependence of closely opposed cyclobutyl pyrimidine dimers induced by UV radiation.
  • 17
Enzymatic processing of radiation-induced free radical damage in DNA.
  • S. Wallace
  • Chemistry, Medicine
  • Radiation research
  • 1998
  • 312
...
1
2
3
4
5
...