Bisphosphonates induced Osteonecrosis of the Jaw: A review

Abstract

Bisphosphonate therapy is used extensively to treat osteoporosis and osteolytic bone lesions. Recently, a special form of osteonecrosis limited to the maxillofacial skeleton has been discovered especially with the use of IV nitrogen containing Bisphosphonates. Bisphosphonates accumulate almost exclusively in maxillofacial skeleton due to high bone turnover… (More)

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