Bisphosphonates and esophageal cancer—a pathway through the confusion

  title={Bisphosphonates and esophageal cancer—a pathway through the confusion},
  author={William Gregory Dixon and Daniel H. Solomon},
  journal={Nature Reviews Rheumatology},
Two recent papers that examined the association between oral bisphosphonates and the risk of esophageal cancer reported seemingly discrepant findings, despite both studies using data from the UK General Practice Research Database, from similar time periods. Each paper set out brief conclusions within their abstracts, generating two opposing impressions: that the risk of incident esophageal cancer is not significantly increased with bisphosphonate use, or that the risk is increased when… CONTINUE READING

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