Bisphosphonate therapy in fibrous dysplasia.

  title={Bisphosphonate therapy in fibrous dysplasia.},
  author={Joseph M. Lane and Safdar N. Khan and William J O'Connor and M. Nydick and Jan Pieter Hommen and Robert C Schneider and Emre A Tomin and Jurgen Brand and J. McAuliffe Curtin},
  journal={Clinical orthopaedics and related research},
Fibrous dysplasia is proliferation of fibrous tissue within the bone marrow causing osteolytic lesions and pathologic fractures. Recently, second generation bisphosphonates have shown promise in the treatment of patients with fibrous dysplasia. In the current study, six patients with fibrous dysplasia were treated with either oral alone or oral and intravenous bisphosphonates. The participants were observed for changes in N-telopeptide, pain score, and radiographic changes. In the current study… CONTINUE READING

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