Bisphenol-A rapidly enhanced passive avoidance memory and phosphorylation of NMDA receptor subunits in hippocampus of young rats.

@article{Xu2011BisphenolARE,
  title={Bisphenol-A rapidly enhanced passive avoidance memory and phosphorylation of NMDA receptor subunits in hippocampus of young rats.},
  author={Xiaohong Xu and Tao Li and Qingqing Luo and Xing Hong and Lingdan Xie and Dong Song Tian},
  journal={Toxicology and applied pharmacology},
  year={2011},
  volume={255 2},
  pages={221-8}
}
Bisphenol-A (BPA), an endocrine disruptor, is found to influence development of brain and behaviors in rodents. The previous study indicated that perinatal exposure to BPA impaired learning-memory and inhibited N-methyl-D-aspartate receptor (NMDAR) subunits expressions in hippocampus during the postnatal development in rats; and in cultured hippocampal neurons, BPA rapidly promotes dynamic changes in dendritic morphology through estrogen receptor-mediated pathway by concomitant phosphorylation… CONTINUE READING
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