Bisphenol A induces differentiation of human preadipocytes in the absence of glucocorticoid and is inhibited by an estrogen-receptor antagonist

@inproceedings{Boucher2014BisphenolAI,
  title={Bisphenol A induces differentiation of human preadipocytes in the absence of glucocorticoid and is inhibited by an estrogen-receptor antagonist},
  author={Jonathan G. Boucher and Ad{\'e}le Boudreau and Ella Atlas},
  booktitle={Nutrition & Diabetes},
  year={2014}
}
Background:Obesity is a major health concern in the developed world, and increasing evidence suggests that exposures to common environmental substances may enhance the risk for the development of this disease.Objectives:The current study examines the effect of the ubiquitous plastic monomer bisphenol A (BPA) on the differentiation of primary human preadipocytes in vitro and the role of the estrogen and glucocorticoid receptors.Methods:In this study, the mechanism of BPA-induced adipogenesis in… CONTINUE READING
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