Bisphenol-A acts as a potent estrogen via non-classical estrogen triggered pathways

  title={Bisphenol-A acts as a potent estrogen via non-classical estrogen triggered pathways},
  author={P. Alonso-Magdalena and Ana B Ropero and S. Soriano and M. Garc{\'i}a-Ar{\'e}valo and A. Nadal},
  journal={Molecular and Cellular Endocrinology},
  • P. Alonso-Magdalena, Ana B Ropero, +2 authors A. Nadal
  • Published 2012
  • Medicine, Biology
  • Molecular and Cellular Endocrinology
  • Bisphenol-A (BPA) is an estrogenic monomer commonly used in the manufacture of numerous consumer products such as food and beverage containers. Widespread human exposure to significant doses of this compound has been reported. Traditionally, BPA has been considered a weak estrogen, based on its lower binding affinity to the nuclear estrogen receptors (ERs) compared to 17-β estradiol (E2) as well as its low transcriptional activity after ERs activation. However, in vivo animal studies have… CONTINUE READING

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