Bisphenol A (BPA) and its potential role in the pathogenesis of the polycystic ovary syndrome (PCOS)

@article{Rutkowska2014BisphenolA,
  title={Bisphenol A (BPA) and its potential role in the pathogenesis of the polycystic ovary syndrome (PCOS)},
  author={Aleksandra Rutkowska and Dominik Rachoń},
  journal={Gynecological Endocrinology},
  year={2014},
  volume={30},
  pages={260 - 265}
}
Abstract Polycystic ovary syndrome (PCOS) is the most common and the most heterogeneous endocrine disorder in premenopausal women. Apart from signs of hyperandrogenism such as acne, hirsutism and hair loss, women with PCOS usually present with menstrual irregularities and fertility problems.Additionally, they are often characterized by impaired glucose tolerance, which usually leads to the development of type 2 diabetes mellitus (T2DM). This review article describes current and novel approach… Expand
Bisphenol-A and polycystic ovary syndrome: a review of the literature
TLDR
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TLDR
Lifetime exposure to a soy diet, containing endocrine active phytoestrogens, but not developmental exposure to the endocrine disrupting monomer bisphenol A (BPA), can induce key features of PCOS in the rat, results which support the hypothesis that hormonally active diets may contribute to risk when consumed throughout gestation and post-natal life. Expand
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The purpose of this study was to determine serum bisphenol A (BPA) concentrations using the high-performance liquid chromatography method combined with tandem mass spectrometry in women withExpand
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TLDR
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Serum bisphenol A concentrations correlate with serum testosterone levels in women with polycystic ovary syndrome.
TLDR
The results point to the potential role of BPA in the pathogenesis of the ovarian hyperandrogenism in women with PCOS. Expand
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