Bisphenol A: invisible pollution

@article{Groff2010BisphenolAI,
  title={Bisphenol A: invisible pollution},
  author={Tricia Groff},
  journal={Current Opinion in Pediatrics},
  year={2010},
  volume={22},
  pages={524–529}
}
  • T. Groff
  • Published 1 August 2010
  • Medicine
  • Current Opinion in Pediatrics
Purpose of review Bisphenol A (BPA) is a high volume chemical used in a wide variety of products, including plastic bottles and canned goods. Based on widespread human exposure and endocrine effects observed first in animal studies and now in humans, this chemical is being extensively studied. Most physicians have not had formal teaching regarding human risks from environmental exposures such as BPA. This article aims to provide: 1) a basis for learning about BPA as an environmental exposure… 
Human exposures to bisphenol A: mismatches between data and assumptions
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Evidence is addressed that challenges the assumption that humans metabolize BPA rapidly enough to result in undetectable levels in blood and therefore it is determined that there is a possibility of harm from current exposure levels.
Exposure assessment of endocrine disruptors in bottled drinking water of Lebanon
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Assessment of BPA human exposure and associated health risks from drinking water in Lebanese finds estimated exposure levels are below the reference dose (RfD), but further studies are needed to quantitate exposure from various sources and to investigate EDR contribution to existing epidemics in the country.
Bisphenol A exposure assessment from olive oil consumption
TLDR
The estimated exposure to BPA levels in olive oil samples stored in plastic vs. non-plastic packaging was 1.38% of the EFSA tolerable daily intake, hence there are no concerns about potential health risks from olive oil consumption.
Bisphenol A: Human exposure and neurobehavior.
Exposure to Bisphenol A From Drinking Canned Beverages Increases Blood Pressure: Randomized Crossover Trial
TLDR
It is demonstrated that consuming canned beverage and consequent increase of BPA exposure increase blood pressure acutely and the parameters of the heart rate variability did not show statistically significant differences.
Protection against Neurobehavioral Changes Induced by Bisphenol A during Development in Rats
TLDR
Zn and/or Se can protect against BPA-induced alterations, and co-administration with BPA improved physical and neurobehavioral development as well as performance of pups in the behavioural experiments.
The effects of postnatal exposure to low-dose bisphenol-A on activity-dependent plasticity in the mouse sensory cortex
TLDR
Exposure to very low levels of BPA during a critical period of brain development can have profound consequences for the normal wiring of sensory circuits and their plasticity later in life.
Associations of Bisphenol A Exposure With Heart Rate Variability and Blood Pressure
TLDR
It is observed that urinary BPA was associated negatively with the root mean square of successive differences for heart rate and positively with blood pressure and the odds ratio of showing hypertension was increased.
Oestrogenic Endocrine Disruptors in the Placenta and the Fetus
TLDR
The mechanism and detection methods of estrogenic endocrine disruptors, such as bisphenol A (BPA), organochlorine pesticides (OCPs), diethylstilbestrol (DES) and phthalates (PAEs), and their effects on placenta and fetal health are elaborated in order to raise concerns about the proper use of products containing EDCs during pregnancy and provide a reference for human health.
Effect of bisphenol A on blood glucose, lipid profile and oxidative stress indices in adult male mice
TLDR
The results suggest that BPA exposure might induce hyperglycemia and its complications in adult male mice by induction of oxidative stress.
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