Bispectral analysis of the electroencephalogram predicts conscious processing of information during propofol sedation and hypnosis.

@article{Kearse1998BispectralAO,
  title={Bispectral analysis of the electroencephalogram predicts conscious processing of information during propofol sedation and hypnosis.},
  author={L A Kearse and Carl E. Rosow and Alan M Zaslavsky and P D Connors and Mark Dershwitz and William Denman},
  journal={Anesthesiology},
  year={1998},
  volume={88 1},
  pages={25-34}
}
BACKGROUND The bispectral index (BIS) measures changes in the interfrequency coupling of the electroencephalogram (EEG). The purposes of this study were (1) to determine whether BIS correlates with responses to command during sedation and hypnosis induced by propofol or propofol and nitrous oxide, and (2) to compare BIS to targeted and measured concentrations of propofol in predicting participants' responses to commands. METHODS Twenty volunteers (15 men and 5 women, aged 22-50 yr) were given… CONTINUE READING