Bispecific antibody conjugates in therapeutics.

@article{Cao2003BispecificAC,
  title={Bispecific antibody conjugates in therapeutics.},
  author={Ying Cao and Laura Lam},
  journal={Advanced drug delivery reviews},
  year={2003},
  volume={55 2},
  pages={171-97}
}
Bispecific monoclonal antibodies have drawn considerable attention from the research community due to their unique structure against two different antigens. The two-arm structure of bsMAb allows researchers to place a therapeutic agent on one arm while allowing the other to specifically target the disease site. The therapeutic agent can be a drug, toxin, enzyme, DNA, radionuclide, etc. Furthermore, bsMAb may redirect the cytotoxicity of immune effector cells towards the diseased cells or induce… CONTINUE READING

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