Bison: bisulfite alignment on nodes of a cluster

Abstract

DNA methylation changes are associated with a wide array of biological processes. Bisulfite conversion of DNA followed by high-throughput sequencing is increasingly being used to assess genome-wide methylation at single-base resolution. The relative slowness of most commonly used aligners for processing such data introduces an unnecessarily long delay… (More)
DOI: 10.1186/1471-2105-15-337

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