Bisalbuminuria in an adult with bisalbuminemia and nephrotic syndrome.

@article{Hoang1999BisalbuminuriaIA,
  title={Bisalbuminuria in an adult with bisalbuminemia and nephrotic syndrome.},
  author={M. Hoang and L. Baskin and F. Wians},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={1999},
  volume={284 1},
  pages={
          101-7
        }
}
  • M. Hoang, L. Baskin, F. Wians
  • Published 1999
  • Chemistry, Medicine
  • Clinica chimica acta; international journal of clinical chemistry
Bisalbuminemia (or alloalbuminemia) is a relatively rare hereditary or acquired condition characterized by the presence of two distinct albumin bands, or, less commonly, a single widened albumin band, after agarose gel electrophoresis of serum. Bisalbumins are caused by point- or chain-mutations that occur with a population frequency of 1:10,000 to 1:1000. Although no adverse clinical effects have been attributed to bisalbumins, some albumin variants have altered affinity for steroid hormones… Expand
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The finding of bisalbuminemia did not influence the diagnosis, management, course, or prognosis of chronic kidney disease and the possibility that some physiologic or pharmacologic substances may not bind to abnormal albumin variants as well as they bind to normal albumin should not be discounted. Expand
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Alloalbumins do not seem to be associated with disease, they can be used as markers of migration and provide a model for study of neutral molecular evolution, and can also give valuable molecular information about albumins binding sites, antioxidant and enzymatic properties, as well as stability. Expand
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• Reporting SPE patterns and their implied clinical conditions that may or may not be related to monoclonal gammapthy is controversial;
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