Birthweight and adult health in a population-based sample of Norwegian twins.
@article{Grjibovski2005BirthweightAA,
title={Birthweight and adult health in a population-based sample of Norwegian twins.},
author={Andrej M. Grjibovski and Jennifer R. Harris and Per Minor Magnus},
journal={Twin research and human genetics : the official journal of the International Society for Twin Studies},
year={2005},
volume={8 2},
pages={
148-55
}
}Population-based twin data were used to test (a) whether lower birthweight confers a greater risk of adult health disorders, and (b) whether within-pair birthweight differences in twins explain discordance for health outcomes. The sample consisted of 1201 monozygotic (MZ) male twins, 1048 dizygotic (DZ) male twins, 1679 MZ female twins, 1489 DZ female twins, and 2423 opposite-sex DZ twins, born in Norway between 1967 and 1979. The relationship between birthweight and self-reported health…
16 Citations
Pre- and Perinatal Risk Factors in Adults with Attention-Deficit/Hyperactivity Disorder
- Medicine, PsychologyBiological Psychiatry
- 2012
The Frequency and Clinical Significance of Twin Gestations According to Zygosity and Chorionicity
- MedicineTwin Research and Human Genetics
- 2010
Although monozygosity was shown to be a risk factor for perinatal death and accurate determination of zygosity plays a great role in the future consideration of organ transplantation and twin studies, the value ofZygosity determination along with chorionicity in relation to overall neonatal morbidity was not definite.
The Norwegian Institute of Public Health Twin Study of Mental Health: Examining Recruitment and Attrition Bias
- Medicine, PsychologyTwin Research and Human Genetics
- 2009
Standard genetic twin analyses of indicators of various mental disorders from Q2, validated by diagnostic data from the MHS, did not indicate differences in genetic/environmental covariance structures between participants and nonparticipants in MHS.
Estimating Returns to Birthweight by Placenta Previa
- Medicine
- 2014
The results provide a foundation for policies that target birthweight: returns to birthweight can be substantial, but they depend on the standard of medical care, and a large part of the highly significant correlations between birthweight and non-health outcomes appear to be noncausal.
The Role of Birth Weight in Myopia – The Genes in Myopia Twin Study
- MedicineOphthalmic Research
- 2009
Assessment of a large cohort of Caucasian monozygotic and dizygotic twins that took part in the Genes in Myopia (GEM) twin study found birth weight appears to have little to no role in the development of myopia.
The Norwegian Twin Registry from a Public Health Perspective: A Research Update
- MedicineTwin Research and Human Genetics
- 2012
The importance of the Norwegian Twin Registry (NTR) for research in public health is described and examples from several programs of twin research at the Norwegian Institute of Public Health (NIPH), including the Nordic Twin Study of Cancer, the epigenetics platform, and the large program of research in mental health are provided.
From the Cradle to the Labor Market? The Effect of Birth Weight on Adult Outcomes
- Economics
- 2005
Lower birth weight babies have worse outcomes, both short-run in terms of one year mortality rates and longer run in terms of educational attainment and earnings. However, recent research has called…
Association of low birth weight with myopic refractive error and lower visual acuity in adulthood: results from the population-based Gutenberg Health Study (GHS)
- MedicineBritish Journal of Ophthalmology
- 2018
It is demonstrated that low BW is linked to visual acuity and refractive long-term outcomes long after childhood, and individuals with low BW are more likely to have lower visual acute and a higher myopic refractive error in adulthood.
The Norwegian Institute of Public Health twin program of research: an update.
- MedicineTwin research and human genetics : the official journal of the International Society for Twin Studies
- 2006
An agreement is now in place to centralize the Norwegian twin data into a national Norwegian Twin Registry, and platforms such as those developed within GenomEUtwin, for data standards and data sharing and access are greatly facilitating international collaborations in twin research.
Association of Birth Parameters with Refractive Status in a Sample of Caucasian Children Aged 4–17 Years
- MedicineJournal of ophthalmology
- 2015
Birth weight and appropriateness for gestational age as birth parameters may have an impact on development of all types of refractive errors and the hypermetropic children tended to be small for gestations between 13 and 17 years of age.
References
SHOWING 1-10 OF 49 REFERENCES
Birth weight and risk of angina pectoris: Analysis in Swedish twins
- MedicineEuropean Journal of Epidemiology
- 2004
The results suggest that genetic differences associated with foetal growth and adult risk of CHD may have affected previously reported associations between birth weight and CHD.
Mortality among twins after age 6: fetal origins hypothesis versus twin method
- MedicineBMJ
- 1995
The findings in the present study suggest that the fetal origins hypothesis is not true for the retardation in intrauterine growth in these twin cohorts and that the hypothesis is no threat to the validity of the twin method.
Asthma in adult life--is there an association with birth weight?
- MedicineScandinavian journal of primary health care
- 1998
These epidemiological findings do not lend support to the hypothesis that a reduced birth weight is associated with a "programming" factor for asthma, and environmental factors in childhood seem more important than fetal malnutrition for the development of asthma in adult life.
The association between birth weight and plasma fibrinogen is abolished after the elimination of genetic influences
- MedicineJournal of thrombosis and haemostasis : JTH
- 2003
The findings suggest that the association between birth weight and plasma fibrinogen is abolished after the elimination of genetic influences and therefore that this association has genetic causes, and improvement of intrauterine nutrition may not lower fibr inogen levels in later life.
Genetics of asthma and hay fever in Australian twins.
- MedicineThe American review of respiratory disease
- 1990
Analysis under the assumptions of the classic twin model suggested that there were genetic factors common to asthma and hay fever, with a correlation in genetic liability to the traits of 0.52 for men and 0.65 for women.
Evidence for Genetic Factors Explaining the Birth Weight–Blood Pressure Relation: Analysis in Twins
- MedicineHypertension
- 2000
Intrapair differences in birth weight were negatively and significantly associated with differences in systolic blood pressure at rest and during the reaction time task in dizygotic twins and monozygotic twins, suggesting that genetic factors may play an important role in the association between birth weight and blood pressure.
Studies of twins: can they shed light on the fetal origins of adult disease hypothesis?
- MedicineTwin research : the official journal of the International Society for Twin Studies
- 2003
It is hypothesised that study of twin pregnancies is a more efficient way to identify modifiable maternal factors that influence later health than studies of singleton pregnancies and that findings in monochorionic twins need to be interpreted with caution.
Population based, controlled study of behavioural problems and psychiatric disorders in low birthweight children at 11 years of age
- Medicine, PsychologyArchives of disease in childhood. Fetal and neonatal edition
- 2002
An increased risk of behavioural problems and psychiatric disorders persists in LBW adolescents, and was as common in those with birth weight less than 1500 g as those withBirth weight 1500–2000 g.
The foetal origins of adult disease: interpreting the evidence from twin studies.
- BiologyTwin research : the official journal of the International Society for Twin Studies
- 2001
Twin studies to date have raised more questions about the foetal origins hypothesis than they have resolved and studies exploring the effect of zygosity and chorion type on later disease provide may provide a useful extension of the research agenda.
Birth weight, body mass index and asthma in young adults
- MedicineThorax
- 1999
Impaired fetal growth and adult fatness are risk factors for adult asthma.


