Birth of parthenogenetic mice that can develop to adulthood.

Abstract

Only mammals have relinquished parthenogenesis, a means of producing descendants solely from maternal germ cells. Mouse parthenogenetic embryos die by day 10 of gestation. Bi-parental reproduction is necessary because of parent-specific epigenetic modification of the genome during gametogenesis. This leads to unequal expression of imprinted genes from the… (More)

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@article{Kono2004BirthOP, title={Birth of parthenogenetic mice that can develop to adulthood.}, author={Tomohiro Kono and Yayoi Obata and Quiong Wu and Katsutoshi Niwa and Yukiko Ono and Yuji Yamamoto and Eun-sung Park and Jeong-Sun Seo and Hidehiko Ogawa}, journal={Nature}, year={2004}, volume={428 6985}, pages={860-4} }