Birth of a gene: locus of neuronal BC200 snmRNA in three prosimians and human BC200 pseudogenes as archives of change in the Anthropoidea lineage.

@article{Kuryshev2001BirthOA,
  title={Birth of a gene: locus of neuronal BC200 snmRNA in three prosimians and human BC200 pseudogenes as archives of change in the Anthropoidea lineage.},
  author={Vladimir Yu Kuryshev and Boris V. Skryabin and Joachim Kremerskothen and Jerzy Jurka and J{\"u}rgen Brosius},
  journal={Journal of molecular biology},
  year={2001},
  volume={309 5},
  pages={1049-66}
}
The gene encoding brain-specific dendritic BC200 small non-messenger RNA is limited to the primate order and arose from a monomeric Alu element. It is present and neuronally expressed in all Anthropoidea examined. By comparing the human sequence of about 13.2 kb with each of the prosimian (lemur 14.6 kb, galago 12 kb, and tarsier 13.8 kb) orthologous loci, we could establish that the BC200 RNA gene is absent from the prosimian lineages. In Strepsirhini (lemurs and lorises), a dimeric AluJ-like… CONTINUE READING

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