Birth of a cohort — the first 20 years of the Raine study

  title={Birth of a cohort — the first 20 years of the Raine study},
  author={Charlotte M. McKnight and John P. Newnham and Fiona Stanley and Jenny A. Mountain and Louis I. Landau and Lawrence J. Beilin and Ian B Puddey and Craig E. Pennell and David Mackey},
  journal={Medical Journal of Australia},
n Th se I the beginning there was an idea ... and funding. e project might never have started if not for a rendipitous meeting between an accountant for the Raine Medical Research Foundation and a young obstetrician. The Foundation had been established 30 years earlier by the bequest of Mary Raine (Box 1), a successful businesswoman who left her property empire to the University of Western Australia (UWA) for medical research. The accountant mentioned that the Foundation had decided to award a… 
The Raine study had no evidence of significant perinatal selection bias after two decades of follow up: a longitudinal pregnancy cohort study
The Raine Study is valuable for association studies, even after 20 years of cohort reviews with increasing non-participation of cohort members, and exposure-outcome association analyses suggest that there is no apparent resulting selection bias.
Data linkage in an established longitudinal cohort: the Western Australian Pregnancy Cohort (Raine) Study.
By linking educational outcomes to the Raine Study database, it was shown across three different age groups that a healthy diet was consistently associated with higher academic performance.
Longitudinal Intergenerational Birth Cohort Designs: A Systematic Review of Australian and New Zealand Studies
This review demonstrates the significant yield from this effort both in terms of scientific discovery and social policy impact and further opportunities have been recognised with cross-study collaboration and pooling of data between established and newer studies and international studies to investigate global health determinants.
Does Otitis Media Affect Later Language Ability? A Prospective Birth Cohort Study.
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The ARCHER study of health and wellbeing in young rural Australians
An overview of preliminary findings from the longitudinal ARCHER (Adolescent Rural Cohort study of Hormones, Health, Education, Environments and Relationships) study of rural adolescent health is provided to provide insight into the specific determinants of health for young people growing up in rural Australia.
Prenatal exposure to maternal stressful life events and earlier age at menarche: the Raine Study.
The observed non-linear U-shape of the association between maternal psychological stress and age at menarche did not reflect a dose-response, which suggests that the first exposure to prenatal stress exerts a greater effect on fetal reproductive development.
Rationale and protocol for the 7- and 8-year longitudinal assessments of eye health in a cohort of young adults in the Raine Study
Eye assessments are being conducted and the data collected will provide an estimate of population incidence and updated prevalence of ocular conditions such as myopia and keratoconus, as well as longitudinal change in ocular parameters in young Australian adults, to allow exploration of the environmental, health and genetic factors underlying inter-subject differential long-term ocular changes.
Clinical cardiovascular risk during young adulthood in offspring of hypertensive pregnancies: insights from a 20-year prospective follow-up birth cohort
Incidence of offspring hypertension was significantly increased in those whose mothers had a more complicated pregnancy history, including preterm birth and pre-eclampsia, which would be proportional to the severity of the pregnancy complication.
The association between in utero exposure to maternal psychological stress and female reproductive function in adolescence: A prospective cohort study
The prevalence and predictors of hypertension in a National Survey of Australian Children
Body mass index is the most important predictor of BP, followed by low socioeconomic status, which means at-risk children may be suitable for screening and intervention studies.


A systematic review of the effect of retention methods in population-based cohort studies
Incentives boosted retention rates in prospective cohort studies and other methods appeared to have a beneficial effect but there was a general lack of a systematic approach to their evaluation.
Retaining and tracking cohort study members.
Approaches for maximizing retention and minimizing loss to follow-up are reviewed, including the importance of communicating the expectations of participation and collecting personal information at baseline, conducting frequent personal and mail contact, and providing incentives for participation.
Methods to increase response rates to postal questionnaires.
The trials evaluated 98 different ways of increasing response rates to postal questionnaires and for 62 of these the combined trials included over 1,000 participants, finding substantial heterogeneity among trial results in half of the strategies.
The 'Trier Social Stress Test'--a tool for investigating psychobiological stress responses in a laboratory setting.
The results suggest that gender, genetics and nicotine consumption can influence the individual's stress responsiveness to psychological stress while personality traits showed no correlation with cortisol responses to TSST stimulation.
Retaining and tracking cohort study
  • members. Epidemiol Rev
  • 1998
A systematic review of the effect of retention methods in populationbased cohort studies
  • BMC Public Health
  • 2011