Bipolar disorder cohort studies: Crucial, but underfunded

  title={Bipolar disorder cohort studies: Crucial, but underfunded},
  author={Eduard Vieta and Jules Angst},
  journal={European Neuropsychopharmacology},
  • E. Vieta, J. Angst
  • Published 22 April 2021
  • Psychology
  • European Neuropsychopharmacology
Biomarkers of neuroprogression and late staging in bipolar disorder: A systematic review.
Current evidence supports the notion of neuroprogression, the pathophysiological process related to progressive brain changes associated with clinical progression in patients with bipolar disorder, and findings indicate a role of peripheral inflammatory markers in this process.
Cognition in older adults with bipolar disorder: An ISBD task force systematic review and meta‐analysis based on a comprehensive neuropsychological assessment
Cognitive dysfunction is present in OABD, with important deficits in almost all cognitive domains, especially in the memory domain, according to a systematic search in MEDLINE/Pubmed, Cochrane, and PsycInfo databases.
Predictors of Functional Impairment in Bipolar Disorder: Results from 13 Cohorts from Seven Countries by The Global Bipolar Cohort Collaborative.
OBJECTIVES Persistent functional impairment is common in bipolar disorder (BD) and is influenced by a number of demographic, clinical, and cognitive features. The goal of this project was to estimate
Genetic Variations Associated with Long-Term Treatment Response in Bipolar Depression
The results suggest that the predictors identified could be useful to guide the pharmacological treatment in bipolar disorder, and an mTOR-related multigenic predictor was associated with a lower number of adverse effects when including switch and autolytical ideation.


Bipolar Disorder.
Brain structural trajectories in youth at familial risk for schizophrenia or bipolar disorder according to development of psychosis spectrum symptoms.
The emergence of psychotic spectrum symptoms in FHR was indexed by smaller cross-sectional surface area and progressive cortical thinning, and relative preservation of surface area over time may signal different processes according to familial risk.
Risk Calculators in Bipolar Disorder: A Systematic Review
The risk calculators reviewed in this article present good discrimination power for bipolar disorder, although future replication and validation of the models is needed.
Machine learning and big data analytics in bipolar disorder: A position paper from the International Society for Bipolar Disorders Big Data Task Force
The International Society for Bipolar Disorders Big Data Task Force assembled leading researchers in the field of bipolar disorder (BD), machine learning, and big data with extensive experience to