Bipolar and major depressive disorder: neuroimaging the developmental-degenerative divide.

Abstract

Both major depressive disorder and bipolar disorder are the subject of a voluminous imaging and genetics literature. Here, we attempt a comprehensive review of MRI and metabolic PET studies conducted to date on these two disorders, and interpret our findings from the perspective of developmental and degenerative models of illness. Elevated activity and… (More)
DOI: 10.1016/j.neubiorev.2009.01.004

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