Bipolar II illness: course and outcome over a five-year period.

  title={Bipolar II illness: course and outcome over a five-year period.},
  author={William H. Coryell and Martin B. Keller and Jean M Endicott and Nancy C. Andreasen and Paula J. Clayton and Robert M. A. Hirschfeld},
  journal={Psychological medicine},
  volume={19 1},
A five year semi-annual follow-up of patients with non-bipolar (N = 442), bipolar II (N = 64) and bipolar I (N = 53) major depression tracked the courses of prospectively observed major depressive, hypomanic and manic syndromes. In all three groups, depression was much more likely in any given week than was hypomania or mania. However, during the majority of weeks, no full syndrome was present and none of the groups exhibited evidence of continuing psychosocial deterioration. Though all three… CONTINUE READING

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