• Corpus ID: 249569323

Bipolar Disorders and Lithium: Pharmacokinetics, Pharmacodynamics, Therapeutic Effects and Indications of Lithium: Review of Articles

@inproceedings{2016BipolarDA,
  title={Bipolar Disorders and Lithium: Pharmacokinetics, Pharmacodynamics, Therapeutic Effects and Indications of Lithium: Review of Articles},
  author={},
  year={2016}
}
  • Published 2016
  • Medicine
Lithium is a mood stabilizer which is approved for use in acute and maintenance mania. It is the first medications approved for the treatment of bipolar disorders. The drug has narrow therapeutic index 0.6-1.2meq/l. The specific mechanism of action of lithium in stabilizing mood is unknown. Alters sodium transport across cell membranes in nerve and muscle cells, It alters metabolism of neurotransmitters including catecholamines and serotonin. May alter intracellular signaling through actions on… 
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Genetic polymorphisms influencing response to lithium in early-onset Bipolar disorder from south India.
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Maternal lithium chloride exposure alters the neuroendocrine‐cytokine axis in neonatal albino rats
  • Dena A. -E. Mohammed, R. Ahmed, R. Ahmed
  • Medicine, Biology
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience
  • 2020
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Maternal LiCl exposure‐induced hypothyroidism disrupts the neonatal neuroendocrine‐cytokine system, which delay cerebral development.

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