Biphenyl synthase from yeast-extract-treated cell cultures of Sorbus aucuparia

  title={Biphenyl synthase from yeast-extract-treated cell cultures of Sorbus aucuparia},
  author={Benye Liu and Till Beuerle and Tim Klundt and Ludger Beerhues},
Biphenyls and dibenzofurans are the phytoalexins of the Maloideae, a subfamily of the economically important Rosaceae. The biphenyl aucuparin accumulated in Sorbus aucuparia L. cell cultures in response to yeast extract treatment. Incubation of cell-free extracts from challenged cell cultures with benzoyl-CoA and malonyl-CoA led to the formation of 3,5-dihydroxybiphenyl. This reaction was catalysed by a novel polyketide synthase, which will be named biphenyl synthase. The most efficient starter… CONTINUE READING


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