Biphasic constrictor response of the rabbit ear artery.

@article{Bevan1971BiphasicCR,
  title={Biphasic constrictor response of the rabbit ear artery.},
  author={John A. Bevan and J. G. Waterson},
  journal={Circulation research},
  year={1971},
  volume={28 6},
  pages={655-61}
}
The perfused rabbit ear artery shows a biphasic contractile response to intraluminal norepinephrine and sympathetic nerve stimulation. The peak of the first phase occurs after approximately 10 seconds of exposure to NE, and the second, after IK to 2 minutes. The magnitudes of the two responses are similar. The time course of the second phase of contraction is similar to the rate of saturation of the vessel's extracellular space as measured by tissue uptake of tritiated norepinephrine. On the… CONTINUE READING
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