Biphasic EEG changes in relation to loss of consciousness during induction with thiopental, propofol, etomidate, midazolam or sevoflurane.

@article{Kuizenga2001BiphasicEC,
  title={Biphasic EEG changes in relation to loss of consciousness during induction with thiopental, propofol, etomidate, midazolam or sevoflurane.},
  author={Kirsten Kuizenga and Jan Mark Klaas Hyltje Wierda and Cor J. Kalkman},
  journal={British journal of anaesthesia},
  year={2001},
  volume={86 3},
  pages={
          354-60
        }
}
The time course of four EEG effect variables, amplitude in the 2-5 Hz and in the 11-15 Hz band, spectral edge frequency 95% (SEF95), and bispectral index (BIS), in response to increasing concentrations of thiopental, propofol, etomidate, midazolam, or sevoflurane during a 10 min induction of anaesthesia was studied in 25 patients to determine the existence of a biphasic effect and to study the relationship of the EEG effect to the moment of loss of consciousness. A biphasic effect, that is, an… CONTINUE READING
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