Bipartite structure of the alpha-lactalbumin molten globule.

@article{Wu1995BipartiteSO,
  title={Bipartite structure of the alpha-lactalbumin molten globule.},
  author={Lawren C. Wu and Zai Yun Peng and Peter S. Kim},
  journal={Nature structural biology},
  year={1995},
  volume={2 4},
  pages={281-6}
}
Molten globules are thought to be general intermediates in protein folding. Apparently conflicting studies have failed to clarify whether one of the best characterized molten globules, that of alpha-lactalbumin, resembles an expanded native-like protein or a nonspecific collapsed polypeptide. Here we show that the molten globule properties of alpha-lactalbumin are largely confined to one of its two domains. The alpha-helical domain forms a helical structure with a native-like tertiary fold… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

Similar Papers

Loading similar papers…