Biotransformation of ginsenosides F4 and Rg6 in zebrafish.

@article{Shen2017BiotransformationOG,
  title={Biotransformation of ginsenosides F4 and Rg6 in zebrafish.},
  author={Wen-wen Shen and Hai-xia Zhang and Shou-Bei Qiu and Ying-jie Wei and Fen-xia Zhu and Jing Wang and Dan-Dan Wang and Xiaobin Jia and Dao-quan Tang and Bin Chen},
  journal={Journal of Asian natural products research},
  year={2017},
  pages={1-11}
}
Ginsenosides F4 and Rg6 (GF4 and GRg6), two main active components of steamed notoginseng or red ginseng, are dehydrated disaccharide saponins. In this work, biotransformation of ginsenosides F4 and Rg6 in zebrafish was investigated by qualitatively identifying their metabolites and then proposing their possible metabolic pathways. The prediction of possible metabolism of ginsenosides F4 and Rg6 using zebrafish model which can effectively simulate existing mammals model was early and quickly… CONTINUE READING
1 Citations
10 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 10 references

Arch

  • B. Chen, Y. J. Wei, D. D. Wang, X. B. Jia
  • Pharm. Res. 38, 1468–1476
  • 2015
Highly Influential
5 Excerpts

Molecules

  • B. Chen, X. B. Jia
  • 18, 8109–8119
  • 2013
Highly Influential
6 Excerpts

Nat

  • B. Chen, Y. P. Shen, D. F. Zhang, J. Cheng, X. B. Jia
  • Prod. Res. 27, 2351–2354
  • 2013
Highly Influential
6 Excerpts

Chin

  • Y. J. Wei, Y. Zhan, C. M. Wang, B. Chen, X. B. Jia
  • JMAP. 30, 461–465
  • 2013

12

  • S. S. Kitambi, E. S. Nilsson, +6 authors BMC Physiol
  • 3–9
  • 2012
1 Excerpt

Acta Pharm

  • Q. X. Chen, S. Zeng
  • Sin. 46, 1026–1031
  • 2011
1 Excerpt

Exp

  • H. Sukardi, H. T. Chng, E. C. Chan, Z. Gong, S. H. Lam
  • Opin. Drug Metab. Toxicol. 7, 579–589
  • 2011
1 Excerpt

Compd

  • E. D. Thompson, K. E. Burwinkel, E. G. Notch, A. K. Chava, G. D. Mayer
  • Biochem. Physiol. C Toxicol. Pharmacol. 152, 371…
  • 2010
1 Excerpt

China J

  • A. Liang
  • Chin. Mater. Med. 34, 2839–2842
  • 2009
1 Excerpt

Curr

  • P. Goldsmith
  • Opin. Pharm. 4, 504–512
  • 2004
1 Excerpt

Similar Papers

Loading similar papers…